Inquire Targeted Sequencing Panel 50 – TSP50™

TSP50™ is a Targeted Sequencing Panel covering 50 genes involved in cancer. This panel is ideal for patients diagnosed with ovarian cancer, breast cancer, prostate cancer and bladder cancer, providing analysis of genes that may offer suitable drug targets.

The TSP50™ panel test can be used as a screening test for diagnosed cancer patients, providing analysis of genes that may offer suitable drug targets.

How is testing performed at EasyDNA?

The panel targets specific regions in 50 genes known to be involved in different cancers:

ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53 and VHL.

DNA is extracted from biopsy or blood samples and testing is performed using Massive Parallel Sequencing (Next Generation Sequencing), which allows highly sensitive mutation detection and gene analysis.

More detailed information on how targeted sequencing of DNA in cancer works can be found here.

What kind of sample is required?

This screening test has been optimised using minimal material (less than 10ng of DNA needed), enabling the use of biopsy samples such as formalin fixed paraffin embedded (FFPE) samples, fine needle aspiration (FNA) samples and cell blocks. The testing can also be performed using blood.

Important:

The TSP50 ™ panel requires genetic counselling from a certified professional and must be handled by a Doctor. Upon confirmation of your order we will send you an email with the Referral forms your doctor or counsellor will complete and return (Fax) to us for approval before your sample collection kit is sent out. The results will be sent directly to the doctor or counsellor who will then discuss them with you.

If you are a family member and/or would like to talk to a genetic counsellor, please contact our customer care team and they will help you to find a qualified professional for the test you are considering.

Medicare rebates may apply.

Note: Your only additional cost will be the blood collection fee that should be arranged with the sample collector during your pathology appointment.